In human history, small organic molecules have been utilized for improving human health and for revealing the secrets of life. Discovery or design of small organic molecules with unique biological activity permits small-molecule-initiated exploration of biology and further understanding of human diseases. Our laboratory has been discovering small organic molecules that modulate gene expression or cellular signaling to use them as tools to explore biology. Such chemistry-initiated biology is recently called chemical biology, an emerging field of biology and medical sciences. Although our chemical biology is a basic one, it may "catalyze" future drug discovery.

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Our laboratory is affiliated with
the Graduate School of Medicine